Positive Amyloid Positron Emission Tomography Findings in a Patient with Recurrent Transient Global Amnesia

Bae, Jaeyeong; Kim, Seungju; Choi, Jae Hyeok; Park, Sungjoo; Yang, Youngsoon

doi:2026.44.4.357

J Korean Neurol Assoc > Volume 44(4); 2026 > Article

Case Report

Journal of the Korean Neurological Association 2026;44(4): 357-361. doi: https://doi.org/10.17340/jkna.2026.0056

재발 일과성전체기억상실 환자에서 동반 확인된 아밀로이드 양전자방출단층촬영 양성 소견

배재영, 김승주, 최재혁, 박성주, 양영순

순천향대학교 의과대학 순천향대학교천안병원 신경과

Positive Amyloid Positron Emission Tomography Findings in a Patient with Recurrent Transient Global Amnesia

Jaeyeong Bae MD, Seungju Kim MD, Jae Hyeok Choi MD, Sungjoo Park MD, Youngsoon Yang MD, PhD

Department of Neurology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea

Corresponding Author: Youngsoon Yang ,Tel: +82-41-570-2290, Fax: +82-41-579-9021, Email: astro76@naver.com

Received: August 14, 2026 Revised: September 4, 2026 Accepted: September 11, 2026 Published online: November 1, 2026

Abstract

A 59-year-old woman had three amnestic episodes at 10- and 11-month intervals; the second was documented only by witness report. Brain magnetic resonance imaging, electroencephalography, and amyloid positron emission tomography (PET) were performed. Diffusion-weighted imaging showed punctate hippocampal lesions, right-sided in the first and left-sided in the third. The Mini-Mental State Examination score remained 29, whereas amyloid PET was visually positive with diffuse cortical deposition. Amyloid pathology may coexist with recurrent transient global amnesia, although its clinical significance remains uncertain.

Key Words: Amnesia | transient global | Amyloid | Positron-emission tomography