Primary Angiitis of the Central Nervous System Diagnosed by
High-Resolution Vessel Wall MRI

J Korean Neurol Assoc > Volume 31(4); 2013 > Article

Journal of the Korean Neurological Association 2013;31(4): 262-265.

고해상도혈관벽MRI로 진단된 중추신경계원발혈관염

조은빈, 김석재 차지훈 a 손태옥 김준표 방오영 김경문 정진상 이광호

성균관대학교 의과대학 삼성서울병원 신경과, 영상의학과 a

Primary Angiitis of the Central Nervous System Diagnosed by High-Resolution Vessel Wall MRI

Eun Bin Cho

Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Radiology and Center for Imaging Science a , Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Abstract

Primary angiitis of the central nervous system (PACNS) is a poorly understood form of vascular inflammatory disease that is restricted to the brain and spinal cord. A 38-year-old woman presented with severe headache and transient aphasia. Her cerebrospinal fluid exhibited aseptic meningitis, and high-resolution vessel-wall MRI (HRVW-MRI) revealed narrowing of multiple intracranial vessels with concentric wall thickening and diffuse enhancement, suggestive of PACNS. High-dose steroid and azathioprine therapy resulted in a significant improvement in vessel wall thickening, and enhancement was observed on the follow-up HRVW-MRI. Key Words: PACNS, Vessel-wall MRI, Therapeutic monitoring