Two Cases of Primary Sjogren's Syndrome Presenting as Relapsing-Remitting Multiple Sclerosis

J Korean Neurol Assoc > Volume 22(4); 2004 > Article

Journal of the Korean Neurological Association 2004;22(4): 410-413.

재발형 다발성경화증처럼 발현한 원발성 Sjogren 증후군 2예

조정희, 김승민 김지현 주종규 이미희 신혜원 도원영 선우일남

연세대학교 의과대학 신경과학교실

Two Cases of Primary Sjogren's Syndrome Presenting as Relapsing-Remitting Multiple Sclerosis

Jeong Hee Cho

Department of Neurology, Yonsei University College of Medicine, Seoul, Korea

Abstract

Sjogren's syndrome is a slowly progressive autoimmune disorder that predominantly affects major exocrine glands, and may also involve the central nervous system (CNS). It is sometimes very difficult to differentiate the CNS Sjogren's syndrome from multiple sclerosis. Here, we report two cases of Sjogren's syndrome who developed variable neurological symptoms mimicking the relapsing-remitting form of multiple sclerosis. There had been several relapses during the course of interferon-beta treatment but no relapses have occurred after steroid maintenance therapy. Key Words: Sjogren's syndrome, Multiple sclerosis