A case of brain metastasis of papillary thyroid carcinoma

J Korean Neurol Assoc > Volume 15(3); 1997 > Article

Journal of the Korean Neurological Association 1997;15(3): 707-711.

갑상선 유두암의 대뇌 전이 1례

김인규, 조연희, 박만석, 김명규, 조기현, 김세종

전남대학교 의대 신경과

A case of brain metastasis of papillary thyroid carcinoma

In Kyu Kim,M.D., Yeon Heoi Cho,M.D., Man Seok Park,M.D., Myeong Kyu Kim, M.D., Ki Hyun Cho, M.D., Sei Jong Kim, M.D.

Department of neurology, College of medicine, chonnam National University

Abstract

Papillary thyroid carcinoma(PTC), the commonest thyroid malignancy, has a good prognosis and low incidence of distant metastasis. Brain metastasis from PTC are extremely rare. The frequency of it reported as 0.1% to 5% in several reported series. A 24 year-old man noted a mass in his neck at 19 years of age. The diagnosis of PTC was made by the biopsy of the mass. Total thyroidectomy, postoperative internal radiation and daily 400w thyroxine therapy was done. The tonic contraction of the right leg evolving to secondary generalized seizure was noted at the age of 24 years old. A brain MRI showed Ix1cm enhancing mass in the left frontal lobe without perilesional edema. The brain mass was removed by the CRW-guided stereotactic surgery. The brain metastasis of PTC was confirmed histopathologically.