Neuropathological Changes in the Subnucleus of Amygdala in ?Alzhemer Disease

J Korean Neurol Assoc > Volume 13(4); 1995 > Article

Journal of the Korean Neurological Association 1995;13(4): 762-766.

알츠하이머병의 편도하핵에서의 신경병리학적 변화

최경규, 박기덕

이화여자대학교 신경과

Neuropathological Changes in the Subnucleus of Amygdala in ?Alzhemer Disease

Kyoung-Gyu Choi, M.D., Ki-Duk Park, M.D.

Department of Neurology, Ewha Woman's University Medical School

Abstract

In this study the quantitative changes of the SP (senile plaque) and NFT (neurofibrillary tangle) in the subnucleus of amygdaloid nucleus were analyzed. All patients (83 cases) were diagnosed clinically and confirmed pathologically as Alzheimer disease. The results were: 1) The SP was most prominenentlv observed in the basomedial sub'nucleus region but NFT was in the lateral subnuclei. 2) There were positive Rank Correlation of pathologic degree between the amygdaloidal subnuclei and neocortex except accessory basal subnuclei. 3)Lateral subnucleus had no Rank Correlation between its SP & NFT.