Three Cases of Generalized Convulsive Status Epilepticus ; As ?Initial Symptom of Nonketotic Hyperglycemia

J Korean Neurol Assoc > Volume 12(4); 1994 > Article

Journal of the Korean Neurological Association 1994;12(4): 740-747.

전신성 경련성 간질중첩증으로 발현된 비케톤성 고혈당증 (증례보고)

이진석, 김진국,김경원,하정숙,하충건,임병훈

경상대학교 신경과.

Three Cases of Generalized Convulsive Status Epilepticus ; As ?Initial Symptom of Nonketotic Hyperglycemia

Jin Seok Lee, M.D., Jin Kook Kim, M.D., Kyeong Won Kim, M.D., Jung Suk Ha, M.D., Choong Kun Ha, M.D., Byeong Hoon Lim, M.D.

Department of Neurology, College of Medicine Gyeongsang National University

Abstract

Status epilepticus is commonly defined as a condition characterized by an epileptic seizure that is so frequently repeated or so prolonged as to produce a fixed and enduring epileptic condition. Common etiologies are brain tumor, CNS infection, vascular insults, trauma, withdrawal of antiepileptic drug, and metabolic disturbance such as hypoglycemia, hypocalcemia, hyponatremia and hyperosmolarity caused by hyperglycemia, hypernatremia, and uremic encephalopathy etc. Although some cases of epilepsia partialis continua in the patient with nonketotic hyperglycemia were reported in the previous literature, we could hardly find the report that generalized convulsive status epilepticus was the initial symptom of nonketotic hypergycemia. We recently experienced three eases of nonketotic hyperglycemia who manifested generalized convulsive status epilepticus as a initial clinical feature. Two cases were completely controlled within a few hours after the correction of hyperglycemia and intravenous dilantinization. Another case was needed an additional phenobarbital administration to control the status epilepticus. In all cases, afterthen no further seizure occurred under the normal serum glucose level without use of antiepileptics.