Postictal Serum Prolactin Alterations in Various Type of Seizures

J Korean Neurol Assoc > Volume 5(2); 1987 > Article

Journal of the Korean Neurological Association 1987;5(2): 124-131.

경련환자의 혈중 Prolactin치의 변동에 관한 연구

유경무, 서성규, 박영춘

계명대학교 신경과.

Postictal Serum Prolactin Alterations in Various Type of Seizures

Kyung-Mu Yoo, M.D., Chung-Kyu Suh, M.D., Young-Choon Park, M.D.

Department of Neurology, Keimyung University School of Medicine

Abstract

Postictal sequential serum prolactin concentrations were observed in 28 patients with various type of seizures who were hospitalized at Keimyung University Hospital. Of 28 epileptic patients, 18 male and 10 female, age ranged from 18 years to 79 years (mean 42 years), 15 with generalized seizures, 13 with focal seizures (5 with simple partial seizures and 8 with partial seizures with generalization). Symptomatic epilepsy and epileptic patients with factors which may affect serum prolactin concentrations were excluded in this study. Serum prolactin concentrations were measure at 15, 30 and 60 minutes after convulsion and 24 hours after convulsion for the base line serum prolactin level. Patients with generalized seizsures and significant elevation of serum prolactin concentrations at 15, 30 and 60 minutes after ictus (Table 1). Same results were obtained in patients with simple partial seizures at 30 minutes and 60 minutes after ictus, and 15 minutes and 30 minutes after ictus in patients with partial seizures with secondary generalization (Table 2 and 3). Level of serum prolactin concentrations were higher in patients with generalized seizure than the other type of seizures. Therefore, measuring serum prolactin level could help differentiate postictal state and other causes of mental change, and also differentiative various type of seizures."