A Case of Dopamine Dysregulation Syndrome with Concurrent Parkinsonism Hyperpyrexia Syndrome

J Korean Neurol Assoc > Volume 25(2); 2007 > Article

Journal of the Korean Neurological Association 2007;25(2): 229-231.

파킨슨병 고열 증후군에 병발한 도파민 조절장애 증후군 1예

노지훈, 이승환a 박건우 이대희 고성범

고려대학교 의과대학 신경과학교실, 강원대학교 의과대학 신경과학교실

A Case of Dopamine Dysregulation Syndrome with Concurrent Parkinsonism Hyperpyrexia Syndrome

Jee Hoon Roh

Department of Neurology, Korea University College of Medicine Department of Neurology, Kangwon National University College of Medicinea

Abstract

A few patients with Parkinson’s disease (PD) crave large amounts of levodopa therapy far beyond those needed to alleviate their symptoms, even in the state of overdose complication. Such harmful pattern of compulsive dopaminergic drug use is called as dopamine dysregulation syndrome (DDS). We report a chronic stage PD patient presenting with high fever and altered mentality, who had the DDS as well as the Parkinsonism hyperpyrexia syndrome (PHS). KeyWords:Parkinson’s Disease, Dopamine Dysregulation Syndrome, Parkinsonism Hyperpyrexia Syndrome