A Case of Postpoliomyelitis Muscular Atrophy

J Korean Neurol Assoc > Volume 6(1); 1988 > Article

Journal of the Korean Neurological Association 1988;6(1): 110-115.

Postpoliomyelitis Muscular atrophy 1예

최진영, 이경덕, 권오상, 민병근, 지제근

중앙대학교 신경과. 서울대학교 병리학.

A Case of Postpoliomyelitis Muscular Atrophy

Jin Yong Choi, M.D., Kyung Duk Lee, M.D., Oh Sang Kwon, M.D.,

Byung Kun Min, M.D., Je Geun Chi, M.D.

Abstract

A relationship between preceding acute paralytic poliomyelitis and the later development of motor neuron disease has only occasionally been suggested since it was first postulated by Charcot in 1875. The authors recently experienced a 20-year-old male who was considered to have postpoliomyelitis muscular atrophy. We report this case in view of its rarity and necessity of differential diagnosis from other neuromuscular disorders. Clinical presentation included slowly progressive muscle wasting of left thigh for 4 years, mild weakness of left arm and both thigh, intermittent fasciculation, and previous history of acute paralytic poliomyelitis. Electromyographic findings showed fibrillation potentials, positive sharp waves, fasciculations, giant motor unit potentials and reduced interference patterns. Muscle biopsy revealed scattered small angulated fibers, individual myofiber degeneration and mild inflammatory cell infiltration.