Myotonic Potentials in the Myopathy Induced by HMG-CoA
Reductase Inhibitor

J Korean Neurol Assoc > Volume 32(3); 2014 > Article

Journal of the Korean Neurological Association 2014;32(3): 186-189.

HMG-CoA환원효소억제제유발근병증에 동반된 근긴장전위

김율희, 김경우 안소현 오미선 마효일 김윤중 이병철

한림대학교 의과대학 신경과학교실

Myotonic Potentials in the Myopathy Induced by HMG-CoA Reductase Inhibitor

Yool-hee Kim

Department of Neurology, Hallym University College of Medicine, Anyang, Korea

Abstract

HMG-CoA reductase inhibitor is widely used for the treatment of dyslipidemia, and for the prevention of stroke and cardiovascular disease. However, it is necessary to consider the adverse effects associated with this drug. Myopathy is a well-known side effect of statin therapy, but myotonic potentials in cases with statin myopathy have thus far been reported only rarely. We report four cases of myopathy with myotonic potentials on electromyography after multidrug administration. All of the patients recovered shortly after statin withdrawal. Key Words: Myotonic potential, HMG-CoA reductase inhibitor, Myopathy