A Case of Multiple Sclerosis Involving Hypothalamus

J Korean Neurol Assoc > Volume 20(2); 2002 > Article

Journal of the Korean Neurological Association 2002;20(2): 191-194.

시상하부를 침범한 다발성경화증 1예

방 현 , 임영민 김광국

울산대학교 의과대학 서울중앙병원 신경과학교실

A Case of Multiple Sclerosis Involving Hypothalamus

Hyun Bang

Department of Neurology, Asan Medical Center, College of Medicine, University of Ulsan

Abstract

"Lesions of multiple sclerosis (MS) are rarely distributed in deep gray matter. We report a case of MS with hypothalamic lesions. A 26-year-old woman with MS developed hyperphagia, hypersomnolence, and amenorrhea. Brain MRI revealed bilateral lesions in both hypothalamus and thalamus. Serum prolactin concentration was increased and thyroid stimulating hormone (TSH) level was decreased. Three months after steroid pulse therapy, her symptoms were completely resolved and prolactin concentration became normal Follow-up brain MRI demonstrated complete disappearance of previous lesions.Key Words : Multiple Sclerosis, Hypothalamus"