Cerebral Metastasis of Malignant Schwannoma (A Case Report)

J Korean Neurol Assoc > Volume 12(3); 1994 > Article

Journal of the Korean Neurological Association 1994;12(3): 577-581.

대뇌전이를 보인 악성 신경초종 1례

이규용, 강성수,권오영,김승현,김주한,김명호

한양대학교 신경과.

Cerebral Metastasis of Malignant Schwannoma (A Case Report)

K.Y. Lee, M.D., S.S. Kang, M.D., O.Y. Kwon, M.D., S.H. Kim, M.D., J.H. Kim, M.D., M.H. Kim, M.D.

Department of Neurology, College of Medicine, Hanyang University

Abstract

Malignant schwannoma is originated from nerve sheath. Its pulmonary and hepatic metastases were reported frequently, but cerebral metastasis was rare. The authors report a case of brain metastasis from a malignant schwannoma arising from left sciatic nerve sheath. Sixtyyear old patient was admitted due to left side hemiparesis. The patient had undergone a surgical resection of the primary tumor in the left thigh. Brain MRI was showed low signal lesion in right frontoparietal area. Microscopically, the neoplasm was composed of spindle cell of neuronal origin that tumor cell was showed herring-bone pattern arrangement with high mitotic activity on high power field. This histologic finding was simialar to that of primary tumor in the left thigh. Immunohistochemically, the tumor shows positive for S-100 protein.