Clinical Course of Myasthenic Patients after Thymectomy and Relationship between Germinal Center and Postoperative Course

J Korean Neurol Assoc > Volume 6(2); 1988 > Article

Journal of the Korean Neurological Association 1988;6(2): 180-185.

중증근무력증 환자에서 흉선절제후의 경과 및 Germinal center와의 관계

김승현, 성기범,김주한,정경천,김명호,박문향

한양대학교 신경과, 병리학.

Clinical Course of Myasthenic Patients after Thymectomy and Relationship between Germinal Center and Postoperative Course

S.H. kim,M.D., K.B. Sung,M.D.,J.H. Kim,M.D., k.C. Chung, M.D., M.H. Kim, M.D.

Department of neurology, College of Medicine, Hanyang University

Abstract

During the follow-up period of 2.2 years in 14 myasthenic patients who had undergohe thymectomy, seven had remission. And four showed enough clinical improvement to reduce their anticholinesterase requirement. No significant change occurred in three patients. Remission of myasthenic symptoms occurred more frequently in patients with few or no germinal centers than those with numerous germinal centers. It is concluded that thymectomy favorably influences the course of the disease in the selected myasthenics, and germinal center may play a role in the prognosis of postoperative course