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J Korean Neurol Assoc. 2013;31(4):270-272.
Cyclosporine-Induced Posterior Reversible Leukoencephalopathy Syndrome With Reduced Cerebral Perfusion
Tae-Ho Kang
Department of Neurology, Pusan National University Hospital, Pusan National University Graduate School of Medicine, Busan, Korea
뇌관류저하를 동반한 시클로스포린 유발 가역적후뇌병증
강태호, 조기용 성상민 정대수 박규현 조한진
부산대학교 의학전문대학원 부산대학교병원 신경과
Abstract
Posterior reversible leukoencephalopathy syndrome (PRLS) is a disorder that is characterized by reversible white-matter edema affecting the posterior regions of the brain. There are rare cases in which cyclosporine has been cited as a medication responsible for PRLS, which causes hypoperfused ischemia by endothelial injury and vasoconstriction, with resultant vasogenic edema. A PRLS patient in whom the condition was induced by cyclosporine is described herein. Perfusion computed tomography revealed a clinically relevant hypoperfused area, including the zones of vasogenic edema. Key Words: Posterior reversible leukoencephalopathy syndrome, Cyclosporine, Perfusion computed tomography

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