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J Korean Neurol Assoc. 2012;30(4):312-315.
- Progressive Multifocal Leukoencephalopathy in a Patient With
Myasthenia Gravis and Thymoma
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Hyun Hee Kang
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Department of Neurology and Pathology
, Samsung Medical Center, Sungkyunkwan University School of Medicine,
Seoul, Korea
Department of Neurology
b
, Seoul National University Bundang Hospital, Seoul National University College of Medicine,
Bundang, Korea
- 중증근무력증과 흉선종 치료 중 발생한
진행다초점백질뇌병증
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강현희, 박재현 이미지 조준훈
서연림
이수진 민주홍 김병준 한석근
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성균관대학교 의과대학 삼성서울병원 신경과, 병리과
a
, 서울대학교 의과대학 분당서울대학교병원 신경과
b
- Abstract
- Progressive multifocal leukoencephalopathy (PML) is a rare and fatal disease caused by JC virus. We report a case of
PML which developed in a 61-year-old female patient with myasthenia gravis (MG) and thymoma. After 6 years of
immunotherapy and chemotherapy she presented with hand weakness followed by progressive decline of
consciousness. Serial brain MRI showed rapidly progressive multifocal white matter changes. The JC virus DNA was
detected on cerebrospinal fluid. This is a third report of PML in MG. Key Words: Myasthenia gravis, Progressive multifocal leukoencephalopathy, Thymoma
Keywords :
- 초록
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