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J Korean Neurol Assoc. 2012;30(2):128-131.
- An Autopsy Case of Amyotrophic Lateral Sclerosis with
Neuroinflammatory change
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Seung Hyun Ha
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Departments of Neurology and Anatomy and Cell Biology
, Hanyang University College of Medicine, Seoul, Korea
- 부검에서 신경염증 변화를 확인한 근위축측삭경화증
환자
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하승현, 백원기 김현영 노민영 황세진
a
김승현
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한양대학교 의과대학 신경과학교실, 해부세포생물학교실
a
- Abstract
- Neuroinflammation such as reactive gliosis and microglial activations are important pathological findings of ALS. We
present a first autopsy case of ALS in Korea related with neuroinflammatory change. A 67-year-old ALS patient suddenly
expired due to accidental head trauma. Gross autopsy finding showed marked atrophic change in spinal cord.
Pathological finding include a marked loss of motor neurons, reactive gliosis and microglial infiltrations. These findings
suggest neuroinflammation may play a role in pathogenesis of ALS. Key Words: Amyotrophic lateral sclerosis, Autopsy, Neuroinflammation
Keywords :
- 초록
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