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J Korean Neurol Assoc. 2010;28(1):56-58.
- 다계통위축의 부검증례
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Jung Hwan Lee
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Department of Neurologya, National Health Insurance Corporation Ilsan Hospital, Koyang, Korea, Department of Neurologyb, Yonsei University College of Medicine, Department of Pathologyc, Yonsei University College of Medicine, Seoul, Korea
- An Autopsy Case of Multiple System Atrophy
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이정환, 송숙근b 김상겸c 김태승c 이필휴b
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국민건강보험공단 일산병원 신경과a, 연세대학교 의과대학 신경과학교실b, 연세대학교 의과대학 병리학교실c
- Abstract
- Multiple-system atrophy (MSA) is an adult-onset, sporadic, progressive neurodegenerative disease. Clinically, the cardinal features include autonomic failure, parkinsonism, cerebellar ataxia, and pyramidal signs in any combination, of which autonomic failure is an integral component in the diagnosis. Pathologically, MSA is characterized by α-synuclein-positive glial cytoplasmic inclusions and neuronal loss, predominantly in the basal ganglia, brainstem, cerebellum, and intermediolateral cell columns of the spinal cord. We report the first case of MSA confirmed by autopsy in Korea. KeyWords:Multiple-system atrophy, Autopsy, Glial cytoplasmic inclusion
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- 초록
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