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J Korean Neurol Assoc. 2009;27(2):110-115.
- The Long-term Incidence of Recurrent Stroke: Single Hospital-based Cohort Study
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Youngchai Ko
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Departments of Neurology, Neurosurgerya, Radiologyb, and Rehabilitation Medicinec, Seoul National University College
of Medicine, Stroke center, Seoul National University Bundang Hospital, Seoul, Korea
- 일개 병원기반 코호트에서 관찰한 장기간의 뇌졸중 재발률
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고영채, 박정현 김욱주 양미화 권오기a 오창완a 정철규b 백남종c 한문구 배희준
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분당서울대학교병원 뇌졸중센터 신경과, 신경외과a, 영상의학과b, 재활의학과c
- Abstract
- Background
Recurrent stroke is a major cause of morbidity and mortality among stroke survivors. However, studies of
the long-term prognosis after acute stroke are very rare, especially in Asia. This study aimed to provide estimates of
recurrent stroke rates by age, gender, and subtype of stroke in an unselected cohort of patients hospitalized to a
community-based general hospital due to acute stroke.
Methods
Based on a prospective stroke registry, acute stroke patients were enrolled within 7 days of symptom onset and
followed retrospectively or prospectively for up to 3 years. Information was gathered about stroke recurrence and other
vascular events. The cumulative risk of recurrent stroke was calculated using the Kaplan-Meier method.
Results
Two-thousand and sixty-eight patients were enrolled in this study. The cumulative risks of stroke recurrence
were 2.3%, 5.5%, 8.6%, and 10.0% at 90 days and 1, 2, and 3 years, respectively. The prevalence of stroke recurrence
increased with age and the presence of previous stroke history (p<0.001), but not with gender or stroke subtype.
Conclusions
To the best of our knowledge, this is the first cohort study of stroke recurrence in Korea. Its limitation of
being a single hospital-based study warrants community- or multicenter-based cohort studies to identify high-risk
groups for stroke recurrence. Key Words: Cerebrovascular disorders, Epidemiology, Recurrence, Stroke outcome
Keywords :
- 초록
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