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J Korean Neurol Assoc. 2009;27(1):28-35.
- One-Year Health Related Quality of Life and Its Comparison With
Various Clinical and Functional Scale in Hospitalized Patients With Acute
Ischemic Stroke: Seoul National University Bundang Stroke Registry Study
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Min-Woo Jo
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Department of Preventive Medicine, University of Ulsan College of Medicine, Seoul, Korea
Department of Neurology, Stroke Center, Seoul National University Bundang Hospital, Seoul, Korea
- 급성 뇌졸중으로 입원한 환자의 1년 후 임상 지표와 건강
관련 삶의 질 비교: 일개 병원 기반의 뇌졸중 등록
체계에 등록된 환자를 중심으로
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조민우, 배희준a
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울산대학교 의과대학 예방의학교실, 분당서울대학병원 뇌졸중센터 신경과a
- Abstract
- Background
Knowing the magnitude of a problem is the first step to improving it, and quantifying the healthrelated
quality of life (HRQOL) allows us to do it with respect to stroke. To identify the HRQOL in patients with
ischemic stroke and its affecting factors, and compare it with other clinical and functional scales.
Methods
A consecutive series of patients with acute ischemic stroke (AIS) or transient ischemic attack (TIA) was
recruited. Their HRQOL and utilities were assessed using the EQ-5Dindex－which evaluates the health profile of an
individual in five dimensions (mobility, self-care, usual activity, pain/discomfort, and anxiety/depression) and
three levels (no problem, some/moderate problems, and extreme problems)－at 1 year after stroke. The Modified
Rankin Scale (MRS), Barthel Index (BI), and NIH Stroke Scale (NIHSS) were used to measure clinical and functional
statuses. The EQ-5Dindex and the clinical and functional statuses were compared by clinical parameters, and the
relationships among those scales were examined. Additionally, the EQ-5Dindex in the patients was compared with
that in age- and sex-matched healthy controls.
Results
Among 538 patients with AIS or TIA, 465 patients (males, 59.8%; age, 65.3±11.8 [mean±SD]; TIA, 7.7%; and
initial NIHSS, 4.5±5.1) were evaluated. The EQ-5Dindex and the clinical and functional statuses were clearly aggravated
by age, but did not differ with most of the risk factors. The EQ-5Dindex was strongly and significantly correlated with
scores on the MRS, BI, and NIHSS. The EQ-5Dindex was lower in patients (especially older ones) than in healthy controls.
Conclusions
This study shows that the EQ-5D is a feasible and valid tool for measuring HRQOL in patients with
AIS or TIA. Key Words: Quality of life, Stroke
Keywords :
- 초록
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