-
-
J Korean Neurol Assoc. 2007;25(3):318-323.
- Neuroimaging of Hemichorea-Hemiballism
-
Sang Hun Yi
-
Department of Neurology, Kyung Hee University College of Medicine, Seoul, Korea;
Department of Nuclear Medicine, Kyung Hee University College of Medicinea, Seoul, Korea
- 반무도병의 신경영상연구
-
이상훈, 안태범 부선희 김덕윤a
-
경희대학교 의과대학 신경과, 경희대학교 의과대학 핵의학과a
- Abstract
- Background
Hemichorea-Hemiballism (HCHB) can be caused by various diseases such as cerebrovascular disease, hyperglycemia, tumor, and inflammatory diseases. However, there are a few case studies using functional imaging such as single photon emission computed tomography (SPECT).
Methods
In this study, we included patients with HCHB. The patients with hyperglycemia over 250 mg/dl or high signal intensity on T1 weighted imaging were excluded. Clinical and neuroimaging characteristics of the patients were obtained and analyzed.
Results
We included 20 patients (M:F=12:8, mean age=67.1±15.3). Sixteen patients were presented with hemiballism and four with hemichorea. Six patients had no structural lesions causing HCHB. Subthalamic nucleus was the causative lesion in 6 patients. Other lesions associated with HCHB were basal ganglia, thalamus, and cortices. In a patient without structural lesion, anti-double stranded DNA antibody was detected. Brain SPECT showed not only perfusion abnormalities in the cases without structural lesions but also additional abnormalities in those with definite lesions.
Conclusions
Various mechanisms were related to the development of HCHB. Functional imaging such as SPECT and immunological work-up is needed to investigate the underlying pathomechanism of HCHB.KeyWords:Hemichorea, Hemiballism, Subthalamic nucleus, SPECT
Keywords :
- 초록
-
