Korean Journal of Sport Science

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J Korean Neurol Assoc. 2006;24(6):581-584.
Two Cases of Metronidazole-Induced Neurotoxicity Lacking of Clinico- Radiological Correlation
Kyum-Yil Kwon
Department of Neurology, University of Ulsan College of Medicine, Seoul, Korea
Metronidazole 중독증: 임상-신경영상 소견의 불일치를 보인 2예
권겸일, 이대균 이가현 조경희 이유진 정선주
울산대학교 의과대학 신경과학교실
Abstract
Metronidazole is an antimicrobial agent widely used for the treatment of trichomoniasis, giardiasis, amebiasis, and anaerobic bacterial infections. It has been reported that metronidazole-induced neurotoxicity is associated with responsible lesions on brain MRI. We report 2 patients with metronidazole-induced neurotoxicity, who had no responsible lesions on brain MRI for their neurological deficits. The pathogenic mechanisms are discussed.KeyWords:Metronidazole, Neurotoxicity, Brain MRI

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