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J Korean Neurol Assoc. 2006;24(4):389-391.
- A Case of Glycyrrhizin (Licorice)-induced Hypokalemic Myopathy
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Beom Joon Kim
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Departments of Neurology and Pathologya, Seoul National University College of Medicine, Seoul, Korea
- 감초 유발성 저칼륨혈증성 근육병증 1예
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김범준, 홍윤호 성정준 박경석 현창림a 최기영a 박성호 이광우
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서울대학교 의과대학 신경과학교실, 병리학교실a
- Abstract
- Glycyrrhizin, the main ingredient of licorice, may evoke severe hypokalemia and muscle paralysis by its mineralocorticoid effects. We present a 78-year-old man who developed subacute flaccid quadriparesis with a high creatine kinase (CK) level, hypokalemia, metabolic alkalosis, and low plasma renin activity after ingesting licorice daily for two years. A muscle biopsy revealed vacuolar degeneration of myofibers. This case suggests that glycyrrhizin (licorice)-induced hypokalemic myopathy must be included in the differential diagnosis of a patient with generalized muscle weakness and hypokalemia.KeyWords:Licorice, Glycyrrhizin, Hypokalemic myopathy, Vacuolar degeneration
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