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J Korean Neurol Assoc. 2005;23(3):313-317.
- Incidence of Patent Foramen Ovale in Ischemic Stroke Patients: A Transcranial Doppler Study
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Dae-Il Chang
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Department of Neurology, Kyunghee University College of Medicine, Seoul, Korea
- 허혈성 뇌졸중 환자에서 난원공개증의 빈도: 경두개초음파 연구
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장대일, 이미숙 조상희 부선희 정세희 허성혁 윤강욱 안태범 윤성상 정경천
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경희대학교 의과대학 신경과학교실
- Abstract
- Background
Patent foramen ovale (PFO) is increasingly being recognized in stroke patients. The capability of transcranial Doppler (TCD) to detect a PFO has been established. We studied the frequency of PFO in patients with ischemic stroke.
Methods
Eighty-nine patients with ischemic stroke (62 men, mean age: 56.5) consecutively underwent a contrast-enhanced TCD with monitoring of the bilateral middle cerebral arteries (MCA). The contrast solution, which consisted of 8 ml of normal saline, 1 ml of air, and 0.2 ml of patient’s blood, was injected twice during normal breathing and the Valsalva maneuver. High intensity transient signals (HITS) were counted for 30 seconds after the injection.
Results
Patent foramen ovale was detected in 19 patients (21%). The mean age was similar in those with (55 years) and those without (57 years) PFO. Patent foramen ovale was more frequent among men (26%) than women (11%). There were no differences in the frequency of PFO among stroke subtypes (large artery atherosclerosis, 18%; small artery occlusion, 27%; cardioembolic, 27%; undetermined cause, 11%).
Conclusions
Patent foramen ovale is common in patients with ischemic stroke of all subtypes.KeyWords:Patent foramen ovale, Ischemic stroke
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- 초록
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