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J Korean Neurol Assoc. 2004;22(3):272-275.
- Anti-Hu Antibody Associated Sensory Neuronopathy Accompanied
by Autonomic Dysfunction
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Young-Eun Park
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Departments of Neurology and Internal Medicine*, Pusan National College of Medicine, University
- 자율신경부전을 동반한 Anti-Hu 항체 양성의 감각신경원병증
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박영은, 주환 김대성 정대수 박규현 이민기
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부산대학교 의과대학 신경과학교실, 내과학교실
- Abstract
- Paraneoplastic sensory neuronopathy may present with autonomic dysfunction resulting either from autonomic neuropathy, or invasion/compression by tumor. We present a 61-year-old female presented with frequent syncope, anhidrosis, and sensory change. Investigations disclosed sensory-autonomic polyneuropathy with positive anti-Hu antibody. The chest computed tomography showed a left mediastinal mass with invasion to the brachiocephalic vein, and a small cell lung cancer was confirmed. She was treated with radiation therapy showing limited improvement. The possible causes of autonomic dysfunction in our patient were discussed.Key Words:Paraneoplastic polyneuropathy, Autonomic nervous system, Small cell carcinoma
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