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J Korean Neurol Assoc. 2004;22(3):255-258.
- A Case of Systemic Lupus Erythematosus Presenting with Chorea:
Evidence for Striatal Hypermetabolism
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Sang Won Ha
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Departments of Neurology and Nuclear Medicine*, University of Ulsan College of Medicine,
Asan Medical Center, Seoul, Korea
- 선조체 대사항진을 보인 무도증으로 발현한 전신성홍반성루푸스 1예
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하상원, 정선주 김재승 임주혁 이명종
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울산대학교 의과대학 신경과학교실, 핵의학과학교실, 서울아산병원
- Abstract
- Chorea is an uncommon clinical manifestation of Sytemic lupus erythematosus (SLE). Its pathogenic mechanism has not been clearly clarified. We report a 54-year-old woman with SLE who presented with generalized chorea as an initial manifestation. Fluorine-18-fluorodeoxyglucose (FDG) PET revealed increased metabolism in the bilateral putamen. Intravenous and oral administration of steroid markedly improved chorea. Hypermetabolism of the bilateral putamen diminished on follow-up FDG-PET after the disappearance of chorea. This study suggests that chorea in SLE is associated with striatal hypermetabolism.Key Words:Chorea, Systemic lupus erythematous (SLE), Fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET)
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