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J Korean Neurol Assoc. 2003;21(5):468-472.
- "Cerebrovascular Reserve Measured by Acetazolamide-challenged
Tc-99m ECD Brain Perfusion SPECT in Symptomatic Internal Carotid Artery
and Middle Cerebral Artery Disease"
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Eun-Hee Kim
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"Department of Neurology and Nuclear Medicine†, School of Medicine, Kyungpook National University,
Department of Neurology, Bugok National Hospital"
- "증후성 내경동맥 및 중뇌동맥 뇌경색 환자에서 Acetazolamide 부하
Tc-99m ECD 뇌관류 SPECT로 측정한 뇌혈관예비능의 비교"
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김은희 , 황양하 안병철 정두교 서정규 박성파
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경북대학교 의과대학 신경과학교실, 핵의학교실†, 국립부곡병원 신경과
- Abstract
- "Background: Hemodynamic evaluation of the brain may be helpful for the identification of a risk of stroke in
patients with middle cerebral artery (MCA) or internal carotid artery (ICA) steno-occlusive disease. The aim of this
study was to evaluate the hemodynamic state in patients with steno-occlusive disease of ICA or MCA on the base of
MRI/MRA and acetazolamide (ACZ)-challenged Tc-99m ECD brain perfusion SPECT findings. Methods: An analysis
of 68 patients who underwent MRI/MRA and ACZ-challenged Tc-99m ECD brain perfusion SPECT was performed.
We divided these patients into two groups - MCA and ICA steno-occlusions. R e s u l t s: The cerebrovascular reserve
(CVR) was impaired in 18 of 32 (56.3%) MCA disease patients (20 stenosis and 12 occlusions), and in 19 of 36
(52.8%) ICA disease patients (20 stenosis and 16 occlusion). The CVR was impaired in 22 of 28 (78.6%) occlusive
patient, whereas in 15 of 40 (37.5%) stenotic patient (p<0.01). The insular lesion was more commonly involved in the
occlusion group (54%) than in the stenosis group (15%) (p<0.01). C o n c l u s I o n s: There was no difference in CVR
between MCA and ICA steno-occlusion groups. Incidence of impaired CVR was higher in occlusion group than stenosis
group.Key Words: Cerebral infarction, Middle cerebral artery, Internal carotid artery, SPECT"
Keywords :
- 초록
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