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J Korean Neurol Assoc. 2003;21(5):461-467.
- "Comparison of Clinical and Neuroradiological Characteristics between
Internal Carotid Artery and Middle Cerebral Artery Occlusive Diseases"
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Se-Ho Oh
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Department of Neurology, College of Medicine, Ajou University
- "중대뇌동맥과 내경동맥 죽상경화증으로 인한 뇌졸중의 임상 및
신경방사선적 양상의 비교"
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오세호 , 이필휴 주성렬 방오영 주인수 허균
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아주대학교 의과대학 신경과학교실
- Abstract
- "Background: The relative importance of embolic mechanisms as opposed to hemodynamic factor in the pathogenesis
of ischemic strokes associated with atherosclerotic middle cerebral artery (MCA) or internal carotid artery (ICA) disease
remains unresolved. We conducted the present study to identify the differences of clinicoradiological patterns
between MCA or ICA diseases. Methods: We defined atherosclerotic disease of MCA or ICA as > 50% stenotic lesions
or ulcerative plaques. We divided the patients into groups of MCA and ICA diseases, and analyzed clinical, laboratory,
and neuroradiological data. R e s u l t s: Among the 620 consecutive patients with acute ischemic strokes, 84 (12.9%)
patients met the criteria for atherosclerotic MCA or ICA disease: 54 patients with MCA disease and 30 patients with
ICA disease. The mean age was younger in patients with MCA than ICA disease (p=0.003). MCA disease clinically
more frequently presented with lacunar syndrome (p=0.001). ICA disease more frequently presented with total anterior
circulation infarct and had higher initial NIHSS scores than MCA disease (p=0.004 and 0.003, respectively). While
whole MCA territorial infarcts were common in ICA disease, deep perforator infarcts were more significantly caused by
MCA disease (p<0.05). MR topographic patterns showed difference between MCA and ICA diseases according to the
degree of stenosis (p<0.05). Cortical dots were significantly accompanied by superficial perforator infarcts than internal
borderzone infarcts (p=0.017). Conclusions: Our present study suggests that clinical and neuroradiological representations
might be different between MCA and ICA diseases, which might reflect difference of underlying pathogenesis.Key Words: Middle cerebral artery , Internal carotid artery, Stenosis, Occlusive disease, Infarction, Artherosclerosis"
Keywords :
- 초록
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