Korean Journal of Sport Science

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J Korean Neurol Assoc. 2003;21(4):432-435.
Myeloneuropathy Following Chronic Abuse of Nitrous Oxide
Young Joo Kwoun
Department of Neurology, College of Medicine, Ewha Womans University
아산화질소의 만성 남용에 의한 척수신경병증 1예
권영주 , 최윤정 오지영 박기덕 최경규
이화여자대학교 의과대학 신경과학교실
Abstract
"Past reports show that chronic abuse has resulted in serious sequalae of myeloneuropathy, optic neuritis and cerebral impairments. A 45-year-old male dentist developed an ascending paresthesia, severe gait ataxia, sensory loss for tactile sensation, proprioception and vibration of the four extremities. Laboratory findings revealed low serum vitamin B12 levels and high levels of homocystein. Our case adds support to previous reports that nitrous oxide could cause neurologic complications by interfering with the utilization of vitamin B12. Key Words: Nitrous oxide abuse, Vitamin B12, Myeloneuropathy"

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