- J Korean Neurol Assoc. 2003;21(4):339-345.
- "Prognostic Value of Parent Arterial Lesions in the Patients with Lacunar Syndrome"
- Sung-Yeol Joo
- Department of Neurology, College of Medicine, Ajou University
- 열공성 증후군 환자에서 모동맥 협착의 예후적 의의
- 주성렬 , 오세호 이재혁 허광기 방오영 허균
- 아주대학교 의과대학 신경과학교실
- Abstract
- "Background: It is well known that a lacunar infarction has characteristic clinical features and a relatively good prognosis.
However, the significance of lesions in the parent artery of patients with lacunar syndrome as regard to the prognosis
remains unsettled. Methods: Using the data of consecutive patients with their first ischemic stroke and were followed
longer than 1 year, were divided the patients by their clinical features and the results of the work-up was as follows;
(1) mismatching [MM] group; lacunar syndrome and the presence of parent arterial lesion, (2) large artery
artherosclerosis [LAD]; non-lacunar syndrome and the presence of parent arterial lesion, (3) no determined etiology
[NE]; non-lacunar syndrome without parent arterial lesion, and (4) small artery disease [SAD]; lacunar syndrome without
parent arterial lesion. Patients with a potential source of embolism were excluded from this study. The prognosis
and recurrence rate of patients with the MM group were compared with those of other groups. Results: A total of 176
patients were included; 56 LAD, 62 SAD, 22 MM and 36 NE groups. An unstable hospital course was more frequently
found in LAD than in the other groups. The recurrence rate of the MM group (23%) was significantly higher than that
of SAD (2%), but was similar to that of patients with non-lacunar syndrome (LAD 16%, NE 28%). C o n c l u s I o n s:
Among patients with lacunar syndrome, the prognosis of those with parent arterial lesions was different from those
without lesions. Therefore, a systematic work up of the stroke mechanism may be important in patients with lacunar
syndrome.Key Words: Infarction/Lacunar, Prognosis, Recurrence"
Keywords :