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J Korean Neurol Assoc. 2003;21(3):225-238.
- Basic Electrophysiology of the Electroencephalography
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Seung Bong Hong
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Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine
- 뇌파의 전기생리학
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홍승봉 , 정기영
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성균관대학교 의과대학 삼성서울병원 신경과학교실
- Abstract
- "Although neuroimaging techniques and other diagnostic procedures has been developed, electroencephalography
(EEG) is still very important for the evaluation of various brain diseases and functional studies of human brain. EEG is
formed mainly by spatial and temporal summations of postsynaptic potentials generated from a large population of
pyramidal cells that can be considered as a collection of oscillating dipoles. EEG shows continuous rhythmic oscillation
depending on sleep-waking state. Alpha rhythms are generated in cortical areas acting as epicenters with local spread,
although the precise cellular mechanism is still unknown. It s been known that neurons in the nucleus reticular thalami
are the pacemakers of sleep spindle. Alterations in the circuit of the reticular nuclei-thalamocortical relay neuron-corti-cal
neuron are responsible for generalized spike and wave complexes. At the intracellular level, large paroxysmal depo-larizing
shifts produce focal epileptic spikes. Slow waves of EEG appear to be related to thalamocortical and/or cor-ticothalamic
deafferentation. The interpretation of routine EEG requires a well training from a qualified EEG teacher
and reading adequate amount of EEG under supervision. Frequent misinterpretations of routine EEG have been
observed in both local clinics and general hospitals. The most common findings of normal routine EEG misinterpreted
as abnormal are normal variants and artifacts of various sources. There are considerable variations of normal EEG
rhythms and pseudoepileptiform discharges. Eyeball movements produce prominent or subtle EEG changes over the
frontal regions that are sometimes hard to be differentiated from abnormal slow waves over that region. Systematic
approach was described for a good interpretation of routine EEG.Key Words: Electroencephalography (EEG), Electrophysiology, Pathophysiology, Epileptiform discharges, Normal
variants, EEG artifacts"
Keywords :
- 초록
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