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J Korean Neurol Assoc. 2001;19(4):435-437.
- Two Cases of Simvastatin-induced Acute Myopathy
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Seung Min Kim, M.D., Youn Min Oh, M.D., Il-Nam Sunwoo, M.D., Ki-Jong Park, M.D.*
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"Department of Neurology, Yonsei University Medical College
Department of Neurology, College of Medicine, Gyeongsang National University*"
- Simvastatin에 의한 급성 근병증을 보인 2예
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김승민, 오윤민 선우일남 박기종*
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연세대학교 의과대학 신경과학교실,경상대학교 의과대학 신경과*
- Abstract
- "Among the side effects of simvastatin, elevated liver enzyme or creatine kinase activity has been occasionally report-ed,
but overt myopathy is rare. We report two cases of simvastatin-induced myopathy with usual dosages of simvas-tatin.
Two patients presented with general myalgia, markedly elevated creatine kinase activity, and mild proximal weak-ness.
One patient had been treated with concomitant use of cyclosporine and simvastatin after renal transplantation, and
another patient had diabetic nephropathy. We recommend careful monitoring when myalgia appears in a patient receiv-ing
simvastatin.
J Korean Neurol Assoc 19(4):435~437, 2001
Key Words : Simvastatin, Myopathy, Cyclosporine"
Keywords :
- 초록
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