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J Korean Neurol Assoc. 2000;18(1):119-120.
- A Case of Rhabdomyolysis after Doxylamine Overdose
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Jong-Chul Kim, M.D., Sang-Ahm Lee, M.D.
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Department of Neurology, Asan Medical Center, College of Medicine, Ulsan University
- Doxylamine Succinate 과다복용에 의한 횡문근 융해
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김종철, 이상암
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울산대학교 의과대학 서울중앙병원 신경과
- Abstract
- We report a case of non-traumatic rhabdomyolysis after overdose of doxylamine succinate. A 22-year-old woman with reactive depression had an overdose of doxylamine with suicidal intent. She had decreased mental state, confu-sion, convulsion, vomiting, tachycardia, pupil dilatation, and ocular flutter. Serum creatine phosphokinase concentra-tion was 6,752 IU/L initially, increased to maximum (165,590 IU/L) at the third day, and then rapidly decreased and returned to normal 2 weeks after intoxication. Acute renal failure occurred but was resolved without hemodialysis. Rhabdomyolysis associated with renal failure is a rare but serious complication after doxylamine overdose. J Korean Neurol Assoc 18(1):119~120, 2000
Key Words : Rhabdomyolysis, Doxylamine, Antihistamine, Renal failure
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