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J Korean Neurol Assoc. 1999;17(5):761-763.
- A Case of Marchiafava-Bignami Disease with Reversible Brain MRI
Findings of Corpus Callosal Lesions
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Jae-hoon Joung, M.D., Ki-Bum Sung, M.D., Moo-Young Ahn, M.D.,
Hyun-kil Shin, M.D., Hyung-Kook Park, M.D.
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Department of Neurology, College of Medicine, Soonchunhyang University
- 뇌 자기공명영상상 뇌량 병변의 호전을 보인
Marchiafava-Bignami병 1예
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정재훈, 성기범 안무영 신현길 박형국
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순천향대학교 의과대학 신경과학교실
- Abstract
- Marchiafava-Bignami disease(MBD), characterized by the primary degeneration of the corpus callosum, is a rare
complication of chronic alcoholism. Recently, a few cases of MBD with reversible neuro-imaging abnormalities were
reported. A 58-year-old, chronic alcoholic man was admitted with mental change, dysarthria, and a seizure attack. A
T2-weighted Brain magnetic resonance imaging demonstrated high signal intensities in the body and splenium of the
corpus callosum, multiple white matter, and cortical gray matter. Treatment with a multiple vitamin complex resulted
in a near complete recovery of neurological manifestation. A brain MRI obtained four weeks after admission revealed a
dramatic resolution of previous imaging abnormalities. We report a case of Marchiafava-Bignami disease with
reversible neuro-imaging abnormalities.
J Kor Neurol Ass 17(5):761~763, 1999
Key Words : Chronic alcoholism, Marchiafava-Bignami disease, MRI
Keywords :
- 초록
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