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J Korean Neurol Assoc. 1999;17(5):752-756.
- A Case of Acute Autonomic and Sensory Neuropathy
Accompanied by Respiratory Failure
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Kyung-Pil Park, M.D., Kyu-Hwan An, M.D., Eun-Joo Kim, M.D., Dae-Seong Kim, M.D.,
Dae-Soo Jung, M.D., Kyu-Hyun Park, M.D., Mae-Ja Kim, M.D.*
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Department of Neurology, Pusan National University of Medicine,
Department of Internal medicine, Ulsan Hospital*
- 호흡 부전을 동반한 급성 자율-감각신경병증 1예
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박경필, 안규환 김은주 김대성 정대수 박규현 김매자*
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부산대학교 의과대학 신경과학교실,울산병원 내과*
- Abstract
- Acute autonomic and sensory neuropathy (AASN) is a rare neuropathy characterized by the acute onset of autonomic
dysfunction and objective sensory disturbances. A 33-year-old woman experienced generalized fatigue, urinary reten-tion,
and defecation difficulty with numbness around her mouth followed by a decreased pain sensation over her face
and whole body, and respiratory difficulty with aspiration pneumonia. Neurological examination revealed bilaterally
dilated fixed pupils, loss of sweating and lacrimation, orthostatic hypotension, and decreased sensation of all modalities
with transient mild to moderate motor weaknesses. The muscle weakness may have been responsible for her respiratory
failure as her respiratory distress was resolved in conjunction with improved general muscle power. Although the
pathogenetic mechanism of AASN has been generally believed to be immune-mediated, the absence of immunoglobu-lin
responsiveness and the negative results to various autoantibody tests in our case, raises questions against its autoim-mune
etiology. The patient showed slow progress of overcoming her autonomic dysfunction with relatively persistent
sensory deficits.
J Kor Neurol Ass 17(5):752~756, 1999
Key Words : Acute autonomic and sensory neuropathy, Respiratory failure
Keywords :
- 초록
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