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J Korean Neurol Assoc. 1999;17(5):726-729.
A case of Neuro-Behcet’s disease with CNS lesions confined to multiple cortical areas
Joon-Kyoon Lee, M.D., Joo-Hyuk Im, M.D., Hyun Bang, M.D., Ji-Yeon Ryu, M.D., Myoung Chong Lee, M.D.
Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine
대뇌 피질에 다발성 병변을 가진 신경베체트병 1예
이준균, 임주혁 방준현 류지연 이명종
울산대학교 의과대학 서울중앙병원 신경과
Abstract
We report a patient diagnosed with neuro-Behcet’s disease showing multiple enhancing lesions on a brain MRI that were confined to the cerebral cortex without any involvement of other brain regions. The patient, a 30-year-old man, was admitted because of seizure attacks. He had the symptom triad of recurrent oral ulcer, genital ulcer, and uveitis. Neurologic symptoms included ataxia, dysarthria, and dementia which had progressed over several years. During the hospital course, he underwent a right hemicolectomy due to bowel perforation. A pathological examination showed multiple discrete ulcerations from the cecum to the mid-transverse colon, consistent with Behcet’s colitis. A brain MRI revealed multiple small enhancing lesions distributed over wide areas of the cerebral cortex. To our knowledge, this pattern of lesion distribution has not yet been reported in neuro-Behcet’s disease. J Kor Neurol Ass 17(3):726~729, 1999 Key Words : Neuro-Behcet’s disease, MRI, Multiple cortical lesions

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