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J Korean Neurol Assoc. 1999;17(4):597-601.
- A Case with Cerebral Radiation Necrosis Mimicking Recurrent Brain Tumor
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Sang Mok Lee, M.D., Hak Jae Noh, M.D., Joo Han Kim, M.D., Woon Gyu Park, M.D., Young Joo Lee, M.D., Gyu yong Lee, M.D., Ha Jung Jun, M.D.*
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Department of Neurology and Radiotherapy*, Hanyang University Hospital
- 재발성 뇌종양 양상을 보인 방사선 조사에 의한 뇌조직 괴사 1예
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이상목, 노학재 ·김주한 ·박운규 ·이영주 ·이규용 ·전하정*
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한양대학교 의과대학 신경과학교실,치료방사선과학교실*
- Abstract
- Regardless of an appropriate radiation therapy administered to a patient with a brain tumor, clinical and radiological evidence of progression may still develop because of a recurrence of the tumor and/or radiation necrosis, or even rarely, a radiation induced neoplasm. The evaluation of tumor recurrence and radiation-induced necrosis presents a diagnostic challenge. A thirty eight year old woman was treated for a focal motor seizure on the right side of her face.with a fractionated external beam radiotherapy under the impression of cystic astrocytoma in the left frontoparietal region. After 6 months, she developed a headache, nausea and vomiting, dysphagia, and secondary generalized seizure. A follow-up brain MRI showed a high signal mass lesion in a T2 weighted image and a fluorodeoxyglucose PET revealed hypometabolism in the left frontoparietal lobe, suggesting radionecrosis. It was confirmed as radionecrosis with an expanding edema by open biopsy. We report a cerebral radiation necrosis mimicking recurrent brain tumor.
J Kor Neurol Ass 17(4):596~601, 1999
Key Words : Radiation Necrosis, Brain Tumor, Biopsy
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