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J Korean Neurol Assoc. 1998;16(3):398-401.
- The Transient Syndrome of Headache with Neurologic Deficits and CSF Lymphocytosis
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Sang-Jin Kim, M.D., Kyoung Heo, M.D., Jong-Hwan Kim, M.D., Oeung-Kyu Kim, M.D., Sung-Eun Kim, M.D.
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Department of Neurology, Pusan Paik Hospital, Inje University College of Medicine
- 일시적인 신경학적 손상과 뇌척수액의 림프구증가증을 동반한 두통 1례
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김상진, 허경ㆍ김종환ㆍ김응규ㆍ김성은
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인제대학교 의과대학 신경과학교실
- Abstract
- In 1981, Bartleson et al described seven patients who experienced three to 12 episodes of headache accompanied by neurologic deficits and CSF lymphocytosis. The headache pain was severe and of a type not previously experienced by the patients. The neurologic deficits were temporary, usually lasting hours and at most 3 days. The CSF showed a predominantly lymphocytosis and increased protein. We report a patients of this syndrome. A 39 year-old woman without a history of migraine developed a right-sided severe headache with weakness in the right extremities. Three days earlier she had an upper respiratory infection. At admission she had a fever. Her speech was dysarthric. She had left homonymous hemianopsia, left-sided hemiparesis and hypoesthesia. Lumbar puncture revealed 180 WBCs (90% lymphocytes) and total protein 132 ㎎/㎗. The symptoms and signs cleared completely within 18 hours. Three days later, she experienced left-sided severe headache followed 1 hour later by confusion after cerebral angiogram. Her language showed Wernicke's aphasia. A repeat lumbar puncture revealed similar result to first attack. The symptoms again cleared two days later. She has remained free of symptoms for 28 months. This syndrome is a self-limited condition, but the etiology of this syndrome is unknown. The monophasic nature and a high frequency of an associated fever and viral illness favor infectious origin.
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