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J Korean Neurol Assoc. 1996;14(3):754-760.
- Abnormalties of Ocular Motor Movement in Patients with Parkinson's Disease
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Ki Jong Choi, M.D., Jae Woo Kim, M.D., and Sang Jo Kim, M.D.,
Seong Ryul Kim, M.D.,Kab Jin Kim, M.D.,
Ji Wook Park, M.D., Kyeong Won Park, M.D.
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Department of neurology, College of Medicine, Dong-A University
- 파킨슨씨병에서의 안구운동 이상
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최기종, 김재우, 김상호, 김성률, 김갑진, 박지욱, 박경원
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동아대학교 의과대학 신경과학교실
- Abstract
- OBJECTIVE : We investigated the relationship between the severity of the disease and the abnormality of some ocular movements in parkinson's disease.
BACKGROUND : Disorders of eye movements have been described in diseases of the basal ganglia for over a century and ocular motor deficits of the saccadic and pursuit system have been reported in parkinsonian patients.
METHOD : We studied the electro-oculography of the eye tracking and saccadic movement in 26 patients (11 males, 15 females) with Parkinson's disease. The severity of the disease was divided into two groups by Hoehn & Yahr(H-Y) staging, H-Y stage 1, 2(group A) and H-Y stage 3, 4 (Group B). Some patients antiparkinsonian drugs of L-dopa, dopamine agonist and anticholinergics.
RESULT : The velocity of smooth pursuit and the velocity and latency of saccade were calculated and compared between two groups. Eye tracking test revealed decreased pursuit velocity leading to catch-up saccades, but normal phase relationship between eye and target movement, while saccadic eye movement had increased latency. These results showed more profound severity in more advanced stages of the disease.
CONCLUSION
: We suggest that ocular movement be often chosen as a simple but relevant example of general motor function, as well as criteria for staging of Parkinson's disease and basal ganglia play significant role in ocular movement.
Keywords :
- 초록
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