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J Korean Neurol Assoc. 1995;13(4):833-842.
- Depression Following Unilateral Supratentorial Stroke
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Ae Young Lee, M.D., Chin Sang Chung, M.D., Jae Moon Kim, M.D.
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Department of Neurology, Chungnam National University Medical College and Hospital, Department of Neurology, Samsung Medical Center
- 일측성 천막상부 뇌졸중에 동반된 우울증에 관한 연구
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이애영, 정진상, 김재문
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전남대학교 신경과, 삼성의료원 신경과
- Abstract
- This study examined the factors responsible for depressive mood following unilateral supratentorial stroke. Sixty-two patients were selected f rom the Outpatient Stroke Clinic in Chungnam National University Hospital to evaluate for depression resulting f rom stroke. We measured their mood state with Beck Depression Inventory. The functional state with physical deficits was determined through neurological examination and the Barthel Index. The cognition of patients was screened with the Short Mental Test. Demographic variables, radiologic characteristics, the degree of cognitive impairment, and the severity of physical disability were considered with respect to the BDI score. Using the univariate analysis, the following variables were selected for a multivariate regression anal ;' ysis for prediction of the BDI score: 1) age at stroke onset, 2) interval from the stroke onset to the evaluation, 3) years of education, 4) the cognitive impairment assessed with the Short Mental Test score, 5) the physical disability determined by the Barthel Index, 6) lesion volume of stroke, 7) relative lesion proximity from the frontal poles, 8) bicaudate index, and 9) the degree of white matter changes rated with the Fazekas scale.
We found that the lesion proximity to frontal pole and the severity of physical disability
are the most determinant factors responsible for the degree of depressive mood status
after stroke. The depressive mood was prominent with the 6 months from stroke,
especially for the left-sided stroke and remit over time. These findings suggest that
the post-stroke depression is not a specific phenomenon but a reactive to their linguistic
and physical deficits.
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- 초록
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