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J Korean Neurol Assoc. 1995;13(2):194-198.
- Abnormalities of Coagulation System In Cerebral Infarction
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Dae Il Chang, M.D., Sung Sang Yoon, M.D., Ki Chung Pack, M.D., Sang Soo Yoon, M.D., Kyung Cheon Chung, M.D.
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Department Neurology , Kyung Hee University Hospital
- 뇌경색의 응고계 이상
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장대일, 윤성상, 박기정, 윤상수, 정경천
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경희대학교 신경과
- Abstract
- Objective. To define the abnormalities of coagulation system in cerebral infarction and the effect of aspirin
Background. Toghi et al(1990,1993) suggested that the coagulation system was
enhanced at all stages of cerebral infarction and long term use of antiplatelet medication
in chronic stroke patients was effective in reducing the elevated coagulant proteins level.
Method. We determined fibrinogen, antithrombin III (ATIII), thrombin-antithrombin III
complex(TAT) in plasma from 40 stroke patients - 32 acute (<7days), 18 subacute
(7-30days) and 32 chronic stage (>30days), and compared 14 patients receiving aspirin
from acute stage with 10 patients not receiving aspirin.
Result. The concentrations of fibrinogen and TAT were significantly elevated in acute
and subacute stages, especially in subacute stage(P<0.01), whereas AT-III was
decreased only in acute stage (P
Keywords :
- 초록
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