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J Korean Neurol Assoc. 1995;13(1):109-114.
- A Case of Primary Leptomemngeal Melanoma
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Jong Su Ye, M.D., Hyeong Jun Kim, M.D., Sang Jin Kim, M.D., Jae Hieon Park, M.D., Kyoung Heo, M.D., Hyo Gun Cho, M.D.
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Department of Neurology, College of Medicine, Inje University
- 연수막의 원발성 악성 흑색종 1예
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예종수, 김형준, 김상진, 박재현, 허 경, 조효근
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인제대학교 신경과
- Abstract
- Primary leptomeningeal melanoma is a rare and aggressive tumor that originates from pial melanin-bearing cells typically along the cerebral conveidties or at the. Base of the brain. It has been hypothesi-d that malign-t transformation Of the preexisting precursor cells leads to diffuse infiltration of the meninges by tumor and the onset of neurological symptoms and signs . The typical neurological symptoms and signs include psychiatric disturbances, seizures, and symptoros and signs of raised intracranial pressure secondary to hydrocephalus. Blindness has been reported as a late feature. Radiotherapy and chemotherapy has been using, but prognosis is poor We d be our experience with 24-years-woman m which the diagnosis of primary leptomeningea1 melanoma without melanotic pigmentation of variable areas of the skm was made.
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- 초록
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