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J Korean Neurol Assoc. 1994;12(3):397-409.
- Clinical Study of Benign Childhood Epilepsy with Centro-Temporal ?Spikes
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Young Soo Yoo, M.D., Jeong Geun Lim, M.D., Sang Doe Yi, M.D., Young Choon Park, M.D.
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Department of Neurology, Keimyung University School of Medicine
- 중심-측두부 극파와 동반된 소아기 간질의 임상적 연구
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유영수, 임정근,이상도,박영춘
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계명대학교 신경과.
- Abstract
- This study was retrospectively undertaken to evaluate clinical manifestations, electroencephalographic findings, response to antiepileptic drugs and prognosis of 80 benign childhood epilepsy with centrotemporal spikes (BCECT) patients seen between 1967 and 1993 and followed up for more than 2 years. The age of onset ranges from 3 to 15 years. In 93 percent of patients, seizures appeared between 4 to 12 year-old, with peak of 5 year-old. The main manifestations of partial seizure were hemifacial spasm (53%) and oropharygeal signs (52%) with hypersalivation, abnormal sensation of mouth, gutteral sounds, swallowing difficulty and feeling of suffocation. The types of seizure consist of partial seizure(66%) and partial seizure with secondary generalization (34%).
Distributions of seizure attack were nocturnal sleep (83%), diurnal sleep state(4%) and
waking state (13%). The typical EEG findings were slow diaphasic high voltage
centrotemporal spikes with unilateral (94%) and bilateral foci(6%) with normal
background. In addition to typical EEG findings, there were associated with multifocal
independent sharp-waves (8.9%) and generalized sharp-wave discharges (7.8%). BCECT
patients were well controlled by antiepileptic drugs and had good prognosis. During the
follow-up period (2-17years), we observed that all patient were well adapted to school
and society. Seizures did not occur after adolescent period.
Keywords :
- 초록
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