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J Korean Neurol Assoc. 1992;10(1):89-92.
- Numb-Chin Syndrome in Malignant Hematologic Diseases
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Seung-Han Suk, M.D., Il-Nam Sunwoo, M.D., Seung-Min Kim, M.D., Sung-Ju Lee, M.D., Jee-Sook Lee, M.D., Jee-Sook Hahn, M.D., Yun-Woong Ko, M.D.
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Department of Neurology and Internal Medicine, College of Medicine, Yoensei University
- 악성 혈액질환에서의 Numb-chin 증후군 7예
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석승한, 선우일남,김승민,이선주,한지숙,고윤웅
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연세대학교 신경과, 내과.
- Abstract
- 'Num-chin syndrome', isolated mental neuropathy, is a rare manifestaion of malignant hernatologic diseases, but important sign for early diagnosis and prediction of clinical course and prognosis. Here we report 7 cases of numb-chin syndrome; one in leukemic transformation of malignant lymphoma, one in blastic crisis of chronic myelogenous leukemia and 5 in acute leukemia Two cases of acute leukemia revealed the 'numb-chin sign' in early course of disease before the diagnosis of leukemia and other three in aggravating state of acute leukemia. The therapeutic response and prognosis was poor and 5 cases expired in a few months.
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