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J Korean Neurol Assoc. 1990;8(2):271-279.
- Somatosensory and Brainstem Auditory Evoked Potentials before and After Hemodialysis in Chronic Renal Failure
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Jeong Geun Lim, M.D., Chung Kyu Suh, M.D., Young Choon Park, M.D. Sung Bae Park, M.D.*, Hyun Chul Kim, M.D.*
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Department of Neurology & Internal Medicine*,
Keimyung Uneversity School of Medicine
- 만성 신부전에서 혈액투석 전후의 체감각 및 뇌간청각유발전위의 변화
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임정근, 서정규, 박영춘, 박성배, 김현철
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계명대학교 신경과, 내과.
- Abstract
- For evaluation of the alterations of the somatosensory evoked potentials(SSEP) and the brainstem auditory evoked potentials(BAEP)before and after hemodialysis, SSEP and BAEP were recorded by using a Medelec ST10 Sensor apparatus before the first dialysis and after subsequent dialyses in 30 urernic patients (19 rnen and 11 women)and the results were compared with the normal controls. The duration of subsequent hemodialyses varied from 0.5 to 9 months, with a mean of 3.3 months. To evaluate the effect of single hemodialysis on BAEP, BAEP were recorded before and after a single hemodialysis in another 10 uremic patients. According to the results of the median nerve SSEP, the absolute latencies of all responses and all interpeak latencies before
hemodialysis and the absolute latencies of all responses and N13-N19 interpeak latency
after hemodialysis were significantly delayed compared with normal controls. The
absolute latencies of N9 and P23 were significantly delayed in the perdialysis compared
with the postdialysis. From the BAEP, the absolute latencies of all responses before and
after hemodialysis and the I-V interpeak latency before hernodialysis were significantly
delayed compared with the normal controls, but there were no significant changes
between predialysis and postdialysis. According to the study of BAEP in another group
of 10 uremic patients before and after a single hemodialysis, the absolute latency of
wave IV and the I-III interpeak latency were reduced in the postdialysis compared with
predialysis but there is no statistical signigicance. The above findings suggest that there
are some peripheral or central nervous system dysfunction in chronic renal failure and
these dysfunctions might be improved by regular hemodialysis and/or a single
hemodialysis. Therefore we suggest that SSEP and BAEP are useful tests for early
diagnosis of central and peripheral nervous dysfunction in chronic renal failure and these
tests might be useful in evaIuation of the effect of hemodialysis.
Keywords :
- 초록
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