Korean Journal of Sport Science

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J Korean Neurol Assoc. 1989;7(1):89-94.
A Case of Podophyllin Induced Peripheral Neuropathy
Sang-Soo Lee,M.D., Jae-Kyu Rho,M.D., Kang-Woo Lee,M.D., Choong-Kun Ha,M.D., Sang-Bok Lee,M.D., Ho-Jin Myung,M.D., Je-G. Chi,M.D.
Department of neurology , College of medicine, Seoul National University Department of Pathology , College of medicine, Seoul National University
Podophyllin 국소도포후 발생한 말초신경병증 1예
이상수, 노재규,이광우,하충건,이상복,명호진,지제근
서울대학교 신경과, 병리학.
Abstract
Podophyllin is known as a neurotoxin, We recently observed a 34-year-old woman with podophyllin induced peripheral neuropathy. She was treated with topical podophyllin for perianal multiple condyloma acuminata. One day after application, she complained of G-I symptoms ( abdominal pain, nausea, vomiting, diarrhea), followed by tingling sensation on all extremities. We confirmed peripheral neuropathy with electrophysiologic study and sural nerve biopsy. She has improved on follow-up.

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