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J Korean Neurol Assoc. 1987;5(2):230-235.
- Autonomic Dysfunction Measured by Valsalva Ratio in Parkinson's ?Disease
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Heung-Joon Kim, M.D., Sang-Bok Lee, M.D., Ho-Jin Myung, M.D.
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Department of Neurology, College of Medicine, Seoul National University
- 파킨슨병의 자율신경계 장애-Valsalva Ratio 측정에 의한 연구
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김홍준, 이상복, 명호진
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서울대학교 신경과.
- Abstract
- As a clinical tool to evaluate autonomic dysfunction, ""Valsalva ratio"" was measured in 36 Parkinson's disease patients (15 men, 21 women) and 10 control subjects (4 men, 6 women).
In this study, the Valsalva ratio was defined as the ratio of peak to nadir heart
rate during Valsalva maneuver, namely voluntary and transient breathholding in maximal
inspiration state with subsequent release by the subject. EKG was monitored throughout
the whole process to observe the moment to moment change of heart rate.
The subject group with Parkinson's disease was subdivided by clinical variables
including sex, are, Hoehn and Yahr clinical stage, duration of symptoms, and duration of
therapy with L-dopa containing drugs.
The Valsalva ratio of the subject group as a whole was less than that of the
control group (P<0.05). But the differences of Valsalva ratio between the subgroups
graded by above clinical variables of Parkinson's disease were not statistically
significant.
The clinical applicability of ""Valsalva ratio"" measurement described in this study
was discussed.
Keywords :
- 초록
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