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J Korean Neurol Assoc. 1986;4(2):246-250.
- A Case of Cerebral Venous Thrombosis in Paroxysmal Nocturnal Hemoglobinuria
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Myung-Sik Lee, M.D., Il-Nam Sunwoo, M.D., Sun-Ju Lee, M.D.*
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Department of Neurology & Internal Medicine*, Yonsei University, College of Medicine
- 발작성 야간혈색소뇨증에 동반된 뇌정맥혈전증 1예
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이명식., 선우일남, 이선주
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연세대학교 신경과, 내과.
- Abstract
- Paroxymal nocturnal hemoglobinuria is a kind of intravascular hemolytic anemia due to acquired corpscular defects, and is not rare in this country. The corpscular defect is originated from hematopoietic stem cells, and white blood cells and platelets are also involved. Consequently, the major complications which might affect mortality and morbidity include thrombotic phenomena, especially hepatic and cerebral venous thrombosis.
This is a case report of cerebral venous thrombosis with hemiparesis, seizure and
change of consciousness in paroxysmal nocturnal hemoglobinuria accompanied by
intravascular hemolysis. The diagnosis is confirmed by CT brain scan and cerebral
angiography and the patient is effectively treated with antiplatelets, anticonvulsants and
steroids.
Keywords :
- 초록
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