-
-
J Korean Neurol Assoc. 1985;3(1):40-48.
- Clinical Study of Pontocerebellar Atrophy Based on CT Brain Scan
-
Kwang-Soo Lee, M.D.,Pil-Ja Jo, M.D., Ki-Hwan Kim, M.D., Jin-Soo Kim, M.D., Il-Nam Sun-Woo, M.D.
-
Department of Neurology, Yunse University, Department of Neurology, National Medical Center
- 전산화단층촬영상 뇌교-소뇌 위축을 보인 15예의 임상적 관찰
-
이광수, 선우일남, 김진수, 김기환, 조필자
-
연세대학교 신경과. 국립의료원 신경과.
- Abstract
- The diagnosis of olivopontocerebellar atrophy (OPCA) was previously based on postmortem pathological findings. Recently, however, the various gross anatomical changes of the central nervous system can be defined by the high resolution CT sean, which can make a diagnosis of several degenerative diseases on a clinical basis.
This report analyzes 15 cases who showed significant pontocerebellar degeneration on
the CT brain scan, including 5 cases of serial studies. All cases were Korean and onset was
between 31 to 63 years of age with about 3 time female preponderance. Two patients were in
one family suggesting hereditary process. The initial symptoms were ataxic gait, dysarthria,
paraparesis, dizziness, and tremors in orders. On examination, the most common clinical
maifestations were dysarthria (80%), cerebellar dysfunctions (73.3%) and hyper-reflexia
(73.3%).
Other findings included parapresis, nystagmus, pathological reflexes and hemiparesis.
Characteristically, there were no sensory or mental deficits. The progression of the symptoms
tended to parall the CT scans on serial studies. The evoked potential studies including
brainstem auditory evoked potential revealed no significant abnormalities exept one case who
showed only borderine prolongation of interwave latency between wave 1 and 3. The
responses on antiparkinson regimens were fruitless.
Keywords :
- 초록
-
