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J Korean Neurol Assoc. 1984;2(1):3-13.
- A Clinical Study on Guillain-Barr'e Syndrome
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Jae-Kyoo Rho, M.D., O-Sang Kwon, M.D., Kwang-Ho Lee M.D., Ho-Jin Myong, M.D.
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Department of Neurology, College of Medicine, Seoul National University, Korea
- Guillain-Barr'e 증후군의 임상적 연구
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노재규, 권오상, 이광호, 이상복, 명호진
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서울대학교 신경과.
- Abstract
- Authors reviewed clinical recordings of 102 patients who were diagnosed as Guillain-Barre syndrome from 1979 to 1983 at Seoul National University Hospital. Among them, eighty-five cases were selected for the clinical study of Guillain-Barre syndrome through application of strict diagnostic criteria. And the following results were obtained.
1) There was a male preponderance (2.5:1) and an apparent predilection for the first and the
second decades in this series.
2) Seasonal predilection was in summer and fall over five years. As judged from the uneven
monthly incidence rate in each year, some epidemic tendency is likely to be in Guillain-Barre syndrome.
3) Sixty cases (71%) of this series had a history of antecedental events. The onset of
neuritic symptoms occurred within one week from the preceding events in twenty-nine
cases and one to two weeks in twenty cases.
4) The neuritic symptoms started from lower limbs in fifty cases (59%), upper limbs in
eighteen (21%), cranial nerve distribution in six (7%) and developed nearly simultaneously in eleven (13%).
5) Most of the disabilities of the patients were devided into flaccid paralysis of limbs, cranial
nerve dysfunction, autonomic dysfunction, respiratory difficulty and sensory
abnormalities (paresthesia and myalgia). Autonomic dysfunction was observed in nine
cases (11%), respiratory difficulty in thirty-one (37%), sensory abnormality in thirty-two
(38%), and cranial nerve dysfunction in forty-seven (55%).
6) Authors devided the crainal nerve dysfunction into facial diplegia which was the most
frequent form, bulbar palsy the next, masticatory muscle weakness the third, and
ocular paresis the least.
7) There were two cases of Fisher syndrome (2.4%), three cases of polyneuritis cranialis
(3.5%), and two cases of recurrence (2.4%) in this series.
8) Two cases (2.4%) died of respiratroy and bulbar dysfunction. Five cases (6%) had
residual disability in motor function till six months follow-up ";
Keywords :
- 초록
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