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J Korean Neurol Assoc. 1983;1(1):81-85.
- Brain CT Findings in Wilson Disease
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Bong-Ae Wi, M.D., Jae-Kyue No, M.D.
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Department of Neurology, Seoul National University
- Wilson병의 뇌전산화 단층촬영 소견
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위봉애, 노재규
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서울대학교 신경과.
- Abstract
- Brain computed tomographic findings in 4 cases of Wilson disease were analysed. All subjects were diagnosed by biochemical assays of copper metabolism and presence of Kayser-Fleisher rings. The results were as followings:
1. Brain CT findings were abnormal in all. Low densities in lenticular nuclei were observed in
three cases. Cortical atrophy with ventricular dilatation was observed in three cases.
Cerebellar atrophy was observed in one case. In one case, cerebellar atrophy was revealed as
main feature. In another one, cortical atrophy with ventricular dilattion was revealed as main
feature.
2. After contrast enhancement, faintly enhancing nodules were observed in two cases. One
showed ill-defined enhancing nodules in frontal and parietal areas and the other showed a rim
enhancing nodule with surrounding low density in left frontal area.
3. Neurologic symptoms of the patients were relatively well correlated with their brain CT
findings. Such symptoms did not improved after treatment. It is probably due to irreversible
brain damage.
Keywords :
- 초록
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